ARUP's Laboratory Test Directory

Complement Activity, Alternative Pathway (AH50) : 2005373

Mnemonic: AH50

Methodology: Semi-Quantitative Radial Immunodiffusion
Performed: Varies
Reported: 7-14 days
Specimen Required: Collect: Serum separator tube or plain red.

Specimen Preparation: Allow specimen to clot for one hour at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.3 mL)

Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions: Specimen types other than serum. Refrigerated or room temperature specimens. Specimens left to clot at refrigerated temperature. Specimens exposed to repeated freeze/thaw cycles.

Stability (collection to initiation of testing): After separation from cells: Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval:
Effective April 2, 2012

59 percent normal or greater
Interpretive Data: This test is intended for screening of functional activity of the alternative pathway of the complement system. Abnormal test results can be due to hereditary absence or acquired functional defect in the activity of any of the individual components of the alternative pathway. If test result is abnormal, order specific tests for evaluation of individual components of alternative pathway, including Complement Factor B (ARUP test code 0051720), Complement Factor Bb (ARUP test code 2003042), and Complement Component 3 (ARUP test code 0050150).

Refer to Statement D under Testing Information at http://www.aruplab.com.
CPT Code(s): 86162
Cross References: Alternative Complement Pathway (Complement Activity, Alternative Pathway (AH50)), Alternative Complement Pathway Function (Complement Activity, Alternative Pathway (AH50)), Alternative Pathway - Complement (Complement Activity, Alternative Pathway (AH50))
 
 

 

 

 
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