ARUP's Laboratory Test Directory

deCODE ProstateCancer™ (Genetic Risk Assessment) : 2003326
[ image for: Prostate Cancer Consent Form (Genetic Risk Assessment)]
Prostate Cancer Consent Form (Genetic Risk Assessment)
  


Mnemonic: PROST CAN

Methodology: Polymerase Chain Reaction/Fluorescent Primer/Nucleic Acid Probe
Performed: On request
Reported: 2 to 3 weeks (no later than 8 weeks from receipt of specimen)
Specimen Required: Collect: All specimens must be collected using the Buccal DNA Collector Kit (ARUP Supply #47080). Available online through eSupply using ARUP Connector contact ARUP Client Services at (800) 522-2787.
1. Use gloves to protect the specimen from contamination.
2. Remove the Buccal DNA Collector from the pouch, holding the handle at the base.
3. Move slider cover back if necessary to fully expose the collection paper. Press the collection paper flat against cheek and drag across at least 7 times.


Specimen Preparation: Push cover forward towards the tip of the collector, covering the collection paper. Transport 2 buccal swabs.

Storage/Transport Temperature: Room temperature.

Unacceptable Conditions: This test was validated for patients of European Caucasian descent only; specimens from patients of other ethnicities will be rejected. Swabs other than those provided in the Buccal DNA Collector Kit.

Stability (collection to initiation of testing): Ambient: 30 days; Refrigerated: Unacceptable; Frozen: Unacceptable

Interpretive Data: This test is NOT designed to diagnose prostate cancer, as test results only provide a risk estimate of the likelihood for developing prostate cancer when compared to the general European Caucasian population. Genotype results are provided for each of the targeted 25 single nucleotide polymorphisms (SNPs) associated with prostate cancer risk. Genetic risk for prostate cancer development is reported as relative genetic risk, lifetime risk, and risk for tumor pathological aggressiveness. 
Note: This test is valid for men of European Caucasian descent only as the genetic variants have not been validated in other ethnic groups.  This test is not approved for New York State clients.

This test is referred to deCODE Genetics, Sturlugata 8, IS-101 Reykjavik, Iceland.
CPT Code(s): 83891 Isolation; 83892 Enzymatic digestion; 83898 x25 Amplification; 83896 x25 Nucleic acid probes; 83914 x25 Extension; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
Cross References: Prostate genetic risk (deCODE ProstateCancer™ (Genetic Risk Assessment))
 
 

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org