ARUP's Laboratory Test Directory

Drug Screen, Targeted, Serum or Plasma : 2003254

Mnemonic: TOF SCR SP

Methodology: Qualitative Liquid Chromatography-Time of Flight Mass Spectrometry
Performed: Mon-Fri
Reported: 1-4 days
Specimen Required: Collect: Gray (sodium fluoride/potassium oxalate). Also acceptable: Plain red, green (sodium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation: Remove plasma from cells ASAP or within 2 hours of collection. Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 2 mL) Also acceptable: Serum.

Storage/Transport Temperature: Refrigerated.

Remarks: Cocaine and cocaethylene are more stable in fluoride-preserved plasma than serum.

Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles. Separator tubes. Plasma or whole blood collected in lt. blue (sodium citrate).

Stability (collection to initiation of testing): After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years

Interpretive Data: Drugs covered and range of cutoff concentrations. Note that some drugs are identified based on the presence of unique drug metabolites that are not listed below.

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing.  The concentration must be greater than or equal to the cutoff to be reported as present.  If specific drug concentrations are required, contact the laboratory within two weeks of specimen collection to request confirmation and quantification by a second analytical technique.

For medical purposes only; not valid for forensic use.
 
Drugs/Drug Classes Range of Cutoff Concentrations
Opioids:
buprenorphine, codeine, dihydrocodeine, fentanyl, heroin, hydrocodone, hydromorphone, meperidine, methadone, morphine, oxycodone, oxymorphone, propoxyphene, tapentadol, tramadol
1-25 ng/mL
Stimulants:
amphetamine, cocaine, methamphetamine, MDMA (Ecstasy), MDEA (Eve), MDA
20-40 ng/mL
Sedative-hypnotics:
alprazolam, amobarbital, butalbital, clonazepam, diazepam, flurazepam, lorazepam, midazolam, nordiazepam, oxazepam, pentobarbital, phenobarbital, secobarbital, temazepam, triazolam
25-500 ng/mL
Cannabinoids (11-nor-9-carboxy-THC) 60 ng/mL
Phencyclidine (PCP) 10 ng/mL

CPT Code(s): 80100
Cross References: Pain Management (Drug Screen, Targeted, Serum or Plasma)
 
 

 

 

 
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