ARUP's Laboratory Test Directory

Methylphenidate & Metabolite - Confirmation/Quantitation - Serum or Plasma : 2003114

Mnemonic: METHPHENSP

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed: Mon, Thu
Reported: 1-7 days
Specimen Required: Patient Prep: Collect specimen 1-6 hours after dose administration.

Collect: Gray (sodium fluoride/potassium oxalate). Also acceptable: Plain red, green (sodium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube and freeze within 6 hours of collection. (Min: 1 mL)

Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Remarks:

Unacceptable Conditions: Lt. blue (sodium citrate). Hemolyzed specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 months

Interpretive Data: Drugs Covered: Methylphenidate and ritalinic acid.

Positive Cutoff:
Methylphenidate: 1 ng/mL
                           
Ritalinic acid: 10 ng/mL
                 

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.
CPT Code(s): 80299
Cross References: Attenade (Methylphenidate & Metabolite - Confirmation/Quantitation - Urine), Concerta (Methylphenidate & Metabolite - Confirmation/Quantitation - Serum or Plasma), Daytrana (Methylphenidate & Metabolite - Confirmation/Quantitation - Serum or Plasma), Dexmethylphenidate (Methylphenidate & Metabolite - Confirmation/Quantitation - Urine), Focalin (Methylphenidate & Metabolite - Confirmation/Quantitation - Urine), Metadate (Methylphenidate & Metabolite - Confirmation/Quantitation - Serum or Plasma), Methylin (Methylphenidate & Metabolite - Confirmation/Quantitation - Serum or Plasma), Methylphenidate (Methylphenidate & Metabolite - Confirmation/Quantitation - Serum or Plasma), Pain Management (Methylphenidate & Metabolite - Confirmation/Quantitation - Serum or Plasma), Ritalin (Methylphenidate & Metabolite - Confirmation/Quantitation - Serum or Plasma), Ritalinic Acid (Methylphenidate & Metabolite - Confirmation/Quantitation - Serum or Plasma)
 
 

 

 

 
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