Reference Interval:
By report
|
| Interpretive Data: |
The performance characteristics of this test were determined by ARUP Laboratories, Inc.
| Result
| Interpretation
| | % Fetal RBCs
| The fetal RBC percentage is directly measured by flow cytometry and gives the percentage of fetal RBCs in maternal circulation resulting from recent fetal-maternal hemorrhage. Post-partum, some fetal cells are expected (0.04% plus or minus 0.024%, mean plus or minus SD).
| | Fetal Blood Volume
| Fetal blood volume is the volume of feto-maternal hemorrhage and is calculated from the % Fetal RBCs by multiplying by 50, assuming a maternal blood volume of 5000 mL and a hematocrit of 50%. Post-partum, some feto-maternal hemorrhage is expected (2.0 mL plus or minus 1.2 mL, mean plus or minus SD).
| | RhIg Required
| Given the delivery of an RhD+ fetus from an RhD- mother, the amount of IM RhIg (anti-RhD immunoglobulin) required to avoid sensitization is 10 µg for each mL of feto-maternal hemorrhage.
| | RhIg Vials Required
| Given the delivery of an RhD+ fetus from an RhD- mother, one (1) vial of RhD (300 µg vial administered IM) is recommended when the amount of RhD required is <300 µg. From 300-600 µg, 2 vials are recommended; from 600-900 µg, 3 vials are recommended; from 900-1200 µg, 4 vials are recommended; from 1200-1500 µg, 5 vials are recommended and so forth.
|
|
| Note: |
This test should only be used to detect and quantify the extent of fetomaternal hemorrhage, in pregnant or post-partum women who need to be assessed for Rh immune globulin (e.g. RhoGAM®) or fetal-maternal bleeds.
For routine fetal hemoglobin (Hb F) testing, please order Hemoglobin Evaluation with Reflex to Electrophoresis and/or RBC Solubility (0050610).
|
| CPT Code(s): |
86356 HgB-F
|
Cross References: |
Fetomaternal Bleed by Flow Cytometry (Blood) (Fetal Hemoglobin Determination for Fetomaternal Hemorrhage)
, Kleihauer-Betke Acid Elution for Fetal RBC Detection (Fetal Hemoglobin Determination for Fetomaternal Hemorrhage)
|
|