ARUP's Laboratory Test Directory

B-Cell Immunodeficiency Profile : 0095940
[ image for: Time Sensitive]
Time Sensitive
  


Mnemonic: B-CELL

Methodology: Quantitative Flow Cytometry
Performed: Sun-Sat
Reported: 1-3 days
Specimen Required: Collect: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation: Transport 5 mL whole blood. (Min: 3 mL)

Storage/Transport Temperature: CRITICAL ROOM TEMPERATURE.

Remarks: Specimens must be analyzed within 48 hours of collection.
New York State Clients: Specimens in heparin must be analyzed within 48 hours of collection; specimens in EDTA must be analyzed within 30 hours of collection.

Unacceptable Conditions: Clotted, frozen, or refrigerated specimens. Specimens older than 48 hours.
New York State Clients: Clotted, frozen, or refrigerated specimens. Specimens in heparin that are more than 48 hours old and specimens in EDTA that are more than 30 hours old.

Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
New York State Clients: Ambient: 48 hours in heparin, 30 hours in EDTA; Refrigerated: Unacceptable; Frozen: Unacceptable.
Reference Interval:
Reports include age appropriate reference intervals and interpretation
Components Reference Interval
% IgD By report
% IgM By report
% Total Ig By report
% HLA-DR By report
% CD19 By report
% IgA By report
% IgG By report

Interpretive Data: The B-cell Immunodeficiency Profile measures circulating B-cells (CD19), their surface immunoglobulins (Total Ig, IgG, IgD, IgM, and IgA) and a common HLA class II antigen. The percentage of lymphocytes expressing CD19, various immunoglobulin fractions and HLA-DR may be altered in certain immunologic abnormalities. For example, HLA-DR is absent on B-cells in the bare lymphocyte syndrome (MHC Class II Deficiency).

Refer to Statement A under Testing Information at http://www.aruplab.com.
CPT Code(s): 86356 CD19; 86356 PSIG; 86356 IGA; 86356 IGD; 86356 IGG; 86356 IGM; 86356 HLA-DR
Cross References: Surface Immunoglobulin Expression on B-cells (B-Cell Immunodeficiency Profile)
 
 

 

 

 
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