Reference Interval:
By report
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| Interpretive Data: |
Test Information: HIV-1 Genotype
This assay predicts HIV-1 resistance to protease and reverse transcriptase inhibitor anti-retroviral drugs. The protease gene and codons 1-335 of the reverse transcriptase gene of the viral genome are sequenced using the Viroseq™ HIV-1 Genotyping System kit. Drug resistance is assigned using ViroSeq™ software. The most current resistance algorithm and drug list is available by selecting the Drug Resistance Report above.
This test should be used in conjunction with clinical presentation and other laboratory markers. A patient's response to therapy depends on multiple factors including patient compliance, percentage of resistant virus population, dosing, and drug pharmacology issues. Resistance interpretations may vary with test method.
According to the Viroseq™ HIV-1 Genotyping System software manual, some insertions or deletions may be difficult to detect using this software. This test may not detect minor HIV-1 populations less than 20 percent of the total population.
The performance characteristics of this test were determined by ARUP Laboratories, Inc.
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| Note: |
This test may be unsuccessful if the plasma HIV-1 RNA viral load is less than 1,000 HIV-1 RNA copies per mL of plasma.
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| CPT Code(s): |
87901
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Cross References: |
HIV Drug Resistance (Human Immunodeficiency Virus 1, Genotyping), HIV Genotype (Human Immunodeficiency Virus 1, Genotyping) |
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