ARUP's Laboratory Test Directory

Myelin Associated Glycoprotein (MAG) Antibody, IgM : 0051285

Mnemonic: MAGM ELISA

Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed: Tue, Thu, Sat
Reported: 1-4 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Urine. Contaminated, heat inactivated, hemolyzed, severely lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval:
Less than 1000 TU
Interpretive Data: Detection of IgM autoantibody against myelin associated glycoprotein (MAG) suggests active demyelination in peripheral neuropathy. The possiblity of MAG antibody involvement in a suspected neuropathy may essentially be ruled out if a MAG IgM negative result is obtained. Detection of MAG IgM antibody by ELISA using human MAG (100 kD) antigen is significantly more sensitive and specific than MAG Western blot and IFA assays using primate antigen.

TU=Titer Units

Refer to Statement D under Testing Information at http://www.aruplab.com.
CPT Code(s): 83516
Cross References: MAG Antibody by ELISA (Myelin Associated Glycoprotein (MAG) Antibody, IgM)
 
 

 

 

 
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