Reference Interval:
29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
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| Interpretive Data: |
Centromere antibody is present in 80-90% of individuals with CREST variant scleroderma. This antibody is also seen in 30% of Raynaud patients, 12% of patients with mixed connective-tissue disease, diffuse scleroderma, interstitial pulmonary fibrosis, primary biliary cirrhosis, and in a smaller percent of patients with systemic lupus erythematosus (SLE) and RA.
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| CPT Code(s): |
83516
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Cross References: |
Anti-Centromere Antibody (Centromere Antibody, IgG), Centromere B (Centromere Antibody, IgG) |
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