Reference Interval:
0.89 IV or less: Negative - No significant level of detectable CMV IgM antibody.
0.90-1.09 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - IgM antibody to CMV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
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| Interpretive Data: |
In immunocompromised patients, CMV serology (IgG or IgM antibody titers) may not be reliable and may be misleading in the diagnosis of acute or reactivation CMV disease. The preferred method for diagnosis is culture of virus and/or demonstration of viral antigen in peripheral white cells (buffy coat), bronchoalveolar lavage (BAL) cells, or tissue biopsies.
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| Note: |
This assay should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).
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| CPT Code(s): |
86645
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Cross References: |
CMV (Cytomegalovirus Antibody, IgM), CMV Antibody (Cytomegalovirus Antibody, IgM) |