ARUP's Laboratory Test Directory

APC Resistance Profile with Reflex to Factor V Leiden : 0030192

Mnemonic: APC R

Methodology: Clotting/Polymerase Chain Reaction/Fluorescence Monitoring
Performed: Refer to individual components
Reported: 1-5 days
Specimen Required: Collect: Lt. blue (sodium citrate) AND lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation: Transport 1.5 mL platelet-poor plasma AND 3 mL whole blood. (Min: 1 mL/each)

Storage/Transport Temperature: Plasma: Frozen. Whole Blood: Refrigerated.

Unacceptable Conditions: Plasma: Non-frozen specimens.

Stability (collection to initiation of testing): Plasma: Ambient: 2 hours; Refrigerated: 4 hours; Frozen: 2 weeks
Whole Blood: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable


Reference Interval:
 
Test Number Components Reference Interval
0030127APC Resistance Profile Effective February 21, 2012

2.0 or greater
0097720Factor V Leiden (F5) R506Q Mutation Negative: This sample is negative for factor V Leiden, R506Q mutation.

Note: If APC resistance is normal, then no further testing will be added. If APC resistance is low, then Factor V Leiden by PCR will be added. Additional charges apply.
CPT Code(s): 85307 APC; if reflexed, add 83891 Isolation; 83896 Nucleic acid probes; 83898 Amplification; 83912 Interpretation and report; - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
Cross References: Factor V Leiden Functional Assay with Reflex to PCR (APC Resistance Profile with Reflex to Factor V Leiden)
 
 

 

 

 
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