APC Resistance Profile : ARUP Lab Tests

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APC Resistance Profile : 0030127

Mnemonic: APC RST

Methodology:	Clotting
Performed:	Mon, Wed, Fri
Reported:	1-4 days
Specimen Required:	Collect: Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines. Specimen Preparation: Transfer 1.5 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL) Storage/Transport Temperature: Frozen. Unacceptable Conditions: Serum. Non-frozen or hemolyzed specimens. Stability (collection to initiation of testing): Ambient: 4 hours; Refrigerated: 4 hours; Frozen: 2 weeks

Reference Interval: Effective February 21, 2012 2.0 or greater
Interpretive Data:	Ratios less than or equal to 2.00 suggest APC resistance. This method uses factor V deficient plasma; therefore, APC resistance due to a nonfactor V mutation will not be detected. Extreme factor V deficiency may cause abnormal ratio.
CPT Code(s):	85307
Cross References:	Activated Protein C Resistance (APCR) (APC Resistance Profile), APCR (APC Resistance Profile), Factor V Leiden Functional Assay (APC Resistance Profile), Protein C Resistance (APC Resistance Profile)

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