Reference Interval:
| Test Number
| Components
| Reference Interval
| | | Arsenic, Urine | 0-35.0 µg/L (based on Biological Exposure Index)
| | | Arsenic, Urine (24-hour) | 0-50.0 µg/d
| | | Arsenic per gram of creatinine | No reference interval (µg/g crt)
| | 0020734 | Arsenic, Fractionated, Urine
| | Test Number
| Components
| Reference Interval
| | | As Organic
| Refer to report | | | Arsenic Total Inorganic
| Refer to report | | | Arsenic, Methylated
| Refer to report |
| | | Creatinine (24-hour)
| | Male
| Female
| 3-8 years: 140-700 mg/d
9-12 years: 300-1300 mg/d
13-17 years: 500-2300 mg/d
18-50 years: 1000-2500 mg/d
51-80 years: 800-2100 mg/d
81 years and older: 600-2000 mg/d
| 3-8 years: 140-700 mg/d
9-12 years: 300-1300 mg/d
13-17 years: 400-1600 mg/d
18-50 years: 700-1600 mg/d
51-80 years: 500-1400 mg/d
81 years and older: 400-1300 mg/d
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| Interpretive Data: |
Specific toxic thresholds for arsenic are not well defined. The ACGIH Biological Exposure Index is 35 µg/L for the sum of the inorganic and methylated forms of arsenic. For specimens with a total arsenic concentration between 35-2000 µg/L, fractionation is performed to determine the proportion of organic, inorganic and methylated forms. If low-level chronic poisoning is suspected, the µg/gCRT ratio may be more sensitive than the total arsenic concentration. It may be appropriate to fractionate specimens with a µg/gCRT ratio >30 µg/gCRT despite a total arsenic concentration <35 µg/L; the laboratory will perform this on request.
The organic forms of arsenic, most commonly arsenobetaine, are considered nontoxic and arise primarily from food. Inorganic forms of arsenic [As(III) and As(V)] are most toxic. Methylated forms (MMA and DMA) arise primarily from metabolism of inorganic forms but may also come from dietary sources and are of moderate toxic potential. As this test does not detect all species of arsenic, it is expected that the sum of the organic, inorganic and methylated forms will not equal the total arsenic concentration.
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| Note: |
If total arsenic concentration is between 35-2000 ug/L, then Arsenic, Fractionated, will be added to determine the proportion of organic, inorganic, and methylated forms. Additional charges apply.
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| CPT Code(s): |
82175; if reflexed, add 82175
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Cross References: |
Arsenic/Creatinine Ratio, Random, Urine (Arsenic, Urine with Reflex to Fractionated), As (Arsenic, Urine with Reflex to Fractionated), ASU (Arsenic, Urine with Reflex to Fractionated) |
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